New research published in the Journal of Clinical Oncology finds that the current computer models used to determine breast cancer risk appears to underestimate the true risk in Asian women. Oncologists use computer models to identify women who might have certain genetic mutations which increase their risk of breast and ovarian cancer. Those women deemed by the models to be likely carriers of the BRCA1 and BRCA2 gene mutations are then referred for genetic testing of these genes. The researchers found that the models were highly accurate in predicting the presence of mutations in white women, but falls short when it comes to Asians. It’s yet unclear why this is the case. They suspect that inheritance patterns common in white women may be different in the Asian population. The researchers emphasize the need for further investigation into the genetic variability of different ethnic groups. Full story.
Tags: asian, breast, Cancer, computer, model, white, women


Dr. Steven Chang, the author of DailyDose, is a staff physician with Kosmix RightHealth. Dr. Chang practices Family Medicine at the University of California Davis Medical Center, where his medical interests include both pediatric and geriatric care, public health, gay and lesbian health, and sleep medicine. Dr. Chang trained at the Stanford University affiliated O'Connor Hospital, and was a research fellow at the National Institute of Health. He holds an M.D. from McGill University and a BA in Public Health from Johns Hopkins University.