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Posts Tagged ‘centenarian’

February 3, 2010

‘Longevity Gene’ Slows Decline In Brain Function »

In 2003 researchers from Albert Einstein College of Medicine in New York isolated a gene, called CETP, which is associated with longevity in a population of Ashkenazi Jews. Now, the same researchers have found the gene in an elderly group of racially and ethnically diverse Bronx residents who have been followed for 25 years as a part of the current study on aging. Participants who carried two copies of the favorable CETP gene variant had a 70% reduction in their risk for developing Alzheimer’s disease, compared with participants who carried no copies of this gene. It’s believed that 1 in 5 people carry the CETP gene, but only those who have two copies of it (one from each parent) will inherit its benefits, including an increased likelihood of living to 100 years old. How will this affect us? Scientists are already working on a drug to mimic the effect of the gene. [via Science Daily]

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November 13, 2009

Are Telomeres Still The Key To Longevity? »

Photo: Telomere via WikipediaTelomeres have been a focus of anti-aging research for quite sometime. Unfortunately, no breakthroughs have yet revealed any glimmer of the fountain of youth. Telomeres are pieces of DNA that cap the ends of our chromosomes. Each time a cell divides (which is required for us to stay alive) telomeres get shorter and shorter until they reach a point where division is halted, thus putting bodily cells into a state where they can no longer renew themselves – thus is part of the aging process. However, new research focusing on Ashkenazi Jews has found that those who lived the longest had inherited a hyperactive version of an enzyme called telomerase that is able to rebuild telomeres. “In effect, centenarians tend to have a top-notch body mechanic at work 24/7 repairing the hardware that runs the body, versus a normal person whose body’s cellular control center is left to wear out with time.” Will this startling research lead to future advances in the pursuit of longevity? Only time will tell. [via Yahoo! News]

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November 23, 2008

Children Of Centenarians Live Longer, Healthier »

Boston University researchers report that children of centenarians live longer than their counterparts, and with less risk of heart attacks, strokes, and diabetes. In a study published in the November issue of the Journal of the American Geriatrics Society, researchers found that offspring of centenarians had 78% lower risk of myocardial infarction (heart attack), an 83% lower risk of stroke, and an 86% lower risk of developing diabetes.

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