Irritable bowel syndrome (IBS) is the most commonly diagnosed gastrointestinal disorder, accounting for 25 to 50 percent of all referrals to gastroenterologists. The exact cause is unknown, but researchers at the Institute of Human Genetics in Heidelberg, Germany have discovered a genetic mutation in serotonin receptors of the intestinal tract that may cause the diarrhea which many people with IBS experience. Serotonin is a hormone that is found not only in the central nervous system, but in large abundance in the GI tract. A mutation in a receptor for serotonin can explain GI disturbances, such as diarrhea. This discovery will likely pave the way for future treatments of IBS.
Posts Tagged ‘IBS’
December 11, 2008


Dr. Steven Chang, the author of DailyDose, is a staff physician with Kosmix RightHealth. Dr. Chang practices Family Medicine at the University of California Davis Medical Center, where his medical interests include both pediatric and geriatric care, public health, gay and lesbian health, and sleep medicine. Dr. Chang trained at the Stanford University affiliated O'Connor Hospital, and was a research fellow at the National Institute of Health. He holds an M.D. from McGill University and a BA in Public Health from Johns Hopkins University.