Researchers at the University of California, Irvine have discovered a protein that senses energy usage in our cells. This protein, called SRT1, works in concert with a circadian rhythm protein called CLOCK to regulate our cells’ activities. When the balance between these proteins is disrupted, say by poor sleep or diet patterns, normal cell functions can become upset in the process. This discovery of a link between a protein involved in cell metabolism and one involved in circadian rhythms demonstrates how sleep disturbance can lead to metabolic problems such as obesity, diabetes, and even accelerated aging. Full Story.
Tags: circadian, CLOCK, metabolism, protein, rhythm, SRT1


Dr. Steven Chang, the author of DailyDose, is a staff physician with Kosmix RightHealth. Dr. Chang practices Family Medicine at the University of California Davis Medical Center, where his medical interests include both pediatric and geriatric care, public health, gay and lesbian health, and sleep medicine. Dr. Chang trained at the Stanford University affiliated O'Connor Hospital, and was a research fellow at the National Institute of Health. He holds an M.D. from McGill University and a BA in Public Health from Johns Hopkins University.